---
title: How NASA technology streamlined the calibration process
description: Learn how Setra automated the patented NASA Low Pressure Generator and transformed it into the MicroCal calibrator.
image: https://www.setra.com/hubfs/bigstock-Nasa-Sign-At-The-Kennedy-Space-665360471.jpg
---

**

**

**

- Website Pages
- Products

[![Setra Systems Logo](https://www.setra.com/hubfs/setra-logo.svg "Setra Systems Logo")](https://www.setra.com/)

![drop-down-pressure](https://www.setra.com/hs-fs/hubfs/angle-arrow-pointing-to-right.png?width=15&name=angle-arrow-pointing-to-right.png)

**[Pressure Sensors](https://www.setra.com/product/pressure)**

[Differential Pressure Sensors](https://www.setra.com/product/pressure/differential)

[Absolute Pressure Sensors](https://www.setra.com/product/pressure/absolute)

[Barometric Pressure Sensors](https://www.setra.com/product/pressure/barometric)

[Compound Pressure Sensors](https://www.setra.com/product/pressure/compound)

[Gauge Pressure Sensors](https://www.setra.com/product/pressure/gauge)

[Submersible Pressure Sensors](https://www.setra.com/product/pressure/submersible)

[Vacuum Pressure Sensors](https://www.setra.com/product/pressure/vacuum)

[UHP Pressure Sensors](https://www.setra.com/product/pressure/uhp)

**[Room Pressure Monitors](https://www.setra.com/product/room-pressure-monitors)**

**[Pressure Calibrator](https://www.setra.com/product/calibration/microcal-pressure-calibrator)**

**[Setra CEMS™ Software](https://www.setra.com/cems)**

**[Power Meters & Accessories](https://www.setra.com/product/power-meters)**

**[Particle Counters](https://www.setra.com/product/particle-counters)**

**[Wireless Solution Systems](https://www.setra.com/wireless)**

**[Humidity/Temp Sensors](https://www.setra.com/product/humidity)**

**[Dolan-Jenner Fiber Optics](https://dolan-jenner.com)**

![drop-down-pressure](https://www.setra.com/hs-fs/hubfs/angle-arrow-pointing-to-right.png?width=15&name=angle-arrow-pointing-to-right.png)

**[Building Automation](https://www.setra.com/building-automation)**

[Calibration](https://www.setra.com/building-automation/calibration-equipment)

[HVAC/R OEM](https://www.setra.com/building-automation/hvac-r-oem-applications)

[HVAC/R](https://www.setra.com/building-automation/hvac-applications)

**[Cleanrooms](https://www.setra.com/critical-environments)**

**[Healthcare](https://www.setra.com/critical-environments/healthcare)**

![drop-down-pressure](https://www.setra.com/hs-fs/hubfs/angle-arrow-pointing-to-right.png?width=15&name=angle-arrow-pointing-to-right.png)

**[General Industrial](https://www.setra.com/industrial)**

[Alternative Fuels](https://www.setra.com/general-industrial/vacuum-pressure-in-alternative-fuels)

[Barometric](https://www.setra.com/general-industrial/barometric-pressure-measurement-tools)

[Data Centers](https://www.setra.com/applications/data-centers/pressure-sensors)

[General Industrial OEM](https://www.setra.com/quality-approved-general-industrial-oem-solutions-setra-systems)

[HVAC/R OEM](https://www.setra.com/building-automation/hvac-r-oem-applications)

[Medical](https://www.setra.com/applications/medical-devices/pressure-sensors)

[Off-Highway Vehicles](https://www.setra.com/general-industrial/pressure-transducers-for-off-highway-vehicles)

[Oil & Gas](https://www.setra.com/general-industrial/oil-and-gas-pressure-measurement)

[Process / MFG Tank Level](https://www.setra.com/general-industrial/liquid-level-sensors)

[Test & Measurement](https://www.setra.com/general-industrial/pressure-test-and-measurement)

[Water & Wastewater](https://www.setra.com/general-industrial/liquid-level-sensors-for-water-processing)

**[Semiconductor Manufacturing](https://www.setra.com/semiconductor-manufacturing-pressure-measurement)**

**[Data Centers](https://www.setra.com/applications/data-centers)**

**[Energy Management](https://www.setra.com/energy-management)**

**[Fiber Optics](https://www.setra.com/fiber-optic-illuminators)**

**[Scales](https://www.setra.com/counting-scales-and-laboratory-balances)**

[![setra-nav-logo.png](https://www.setra.com/hs-fs/hubfs/setra-nav-logo.png?width=133&name=setra-nav-logo.png "setra-nav-logo.png")](https://www.setra.com/)

![Menu](https://www.setra.com/hs-fs/hubfs/moble-icon.jpg?width=30&name=moble-icon.jpg)

×

[Home](https://www.setra.com)

Markets >

[Healthcare](https://www.setra.com/critical-environments/healthcare) [Building Automation](https://www.setra.com/building-automation) [Cleanrooms](https://www.setra.com/critical-environments) [General Industrial](https://www.setra.com/industrial) [Semiconductor Manufacturing](https://www.setra.com/semiconductor-manufacturing-pressure-measurement) [Data Centers](https://www.setra.com/applications/data-centers?hsLang=en) [Energy Management](https://www.setra.com/energy-management) [Fiber Optics](https://www.setra.com/fiber-optic-illuminators) [Scales](https://www.setra.com/counting-scales-and-laboratory-balances)

Products >

[Pressure Sensors](https://www.setra.com/product/pressure) [Room Pressure Monitors](https://www.setra.com/product/room-pressure-monitors) [Particle Counters](https://www.setra.com/product/particle-counters) [Setra CEMS™ Software](https://www.setra.com/cems) [Power Meter & Accessories](https://www.setra.com/product/power-meters) [Pressure Calibrator](https://www.setra.com/product/calibration/microcal-pressure-calibrator) [Wireless Solutions Systems](https://www.setra.com/wireless) [Humidity/Temp Sensors](https://www.setra.com/product/humidity) [Dolan-Jener](https://dolan-jenner.com/) 

[OEM Solutions](https://www.setra.com/custom-solutions)

Resources >

[Blog](https://www.setra.com/blog) [Videos](https://www.setra.com/video-resources) [FAQs](https://article.setra.com/) [Compliance](https://article.setra.com/compliance-documents) [Supplier](https://www.setra.com/support/supplier) [Current Customers](https://www.setra.com/support/customer) 

[Order Online](https://ecatalog.setra.com)

Returns >

[Services & Calibration](https://www.setra.com/support/service) [New and Unused for Credit](https://www.setra.com/product-return) 

[Contact Us](https://www.setra.com/help-center)

# How NASA technology streamlined the calibration process

#### by [Tom Lish](https://www.setra.com/blog/author/tom-lish)

- [Tweet](https://twitter.com/share)

 [![How NASA technology streamlined the calibration process - Setra Systems](https://www.setra.com/hs-fs/hubfs/bigstock-Nasa-Sign-At-The-Kennedy-Space-665360471.jpg?width=303&name=bigstock-Nasa-Sign-At-The-Kennedy-Space-665360471.jpg "How NASA technology streamlined the calibration process - Setra Systems")](https://www.setra.com/products/calibration/microcal-advanced-modular-pressure-calibrator)Technicians at the Kennedy Space Center often work in [cleanrooms](https://www.setra.com/blog/sensor-calibration-for-cleanroons), laboratories with high degrees of cleanliness provided by strict control of particles such as dust, lint, or human skin. These facilities must be contaminant-free environments where the air is repeatedly filtered and surfaces are smooth to prevent particles from getting lodged.

Engineers, scientists, and other workers [operating in these environments](https://www.setra.com/blog/how-can-personnel-contaminate-a-clean-environment) wear specially designed cleanroom “bunny suits” and booties over their street clothes, as well as gloves and face masks to avoid any contamination that may be imparted from the outside world. Even normal paper is not allowed in cleanrooms—only cleanroom low particulate paper is permitted. It goes without saying that these spaces are very sensitive environments in where precision work, like the production of silicon chips or hard disk drives, is best performed.

## Why do cleanrooms need to monitor air pressure?

Often in cleanrooms, positive air pressure is used to force particles outside of the isolated area. The air pressure in NASA cleanrooms is monitored using high-accuracy, low-differential pressure transducers that require periodic calibration.

Calibration of the transducers can be a [somewhat tricky endeavor](https://www.setra.com/blog/what-are-the-different-methods-of-low-pressure-calibration). In prior years, the analysis was performed by sending the transducers to the Kennedy Standards Laboratory, where a very expensive cross-floated, labor intensive, dead-weight test was conducted.

## Birth of the Setra MicroCal

[![Setra MicroCal](https://www.setra.com/hs-fs/hubfs/social-suggested-images/MicroCal-MCPM-opened.jpg?width=241&name=MicroCal-MCPM-opened.jpg "Setra MicroCal")](https://www.setra.com/products/calibration/microcal-advanced-modular-pressure-calibrator)In the early 1990s, scientists at NASA determined to develop a technique and test equipment to perform qualification testing on new low-differential pressure transducers in an accurate, cost-effective manner on site, without requiring an environmentally controlled room.

They decided to use the highly accurate, cost-effective [Setra Model 264](https://www.setra.com/products/pressure/model-264-low-differential-pressure-transducer) differential pressure transducer for their testing. For qualification testing of the Setra 264, though, a portable and lower cost calibrator was needed that could control the differential pressure to a high degree of resolution and transfer the accuracy of the Standards Laboratory into the qualification testing.

The researchers decided that to generate the low-differential pressure setpoints needed for qualification testing, very small gas volume changes could be made against the test article, and a corresponding pressure change would be detected by a pressure standard. This allowed the researchers to recreate cleanroom air pressure settings without the use of a cleanroom. By 1995, the prototype was perfected into the unit that is still used today, the [MicroCal](https://www.setra.com/products/calibration/microcal-advanced-modular-pressure-calibrator).

**Want to learn more about the Setra MicroCal? [Take a look through our digital brochure](https://www.setra.com/setra-pressure-calibration-brochure-0?hsCtaTracking=26137f4e-99dd-49e3-b0e5-5f4dbbf8b4eb%7Caa1667b3-c24a-4a60-a565-84a219e16eda).**

 

 Topics: [Critical Environments](https://www.setra.com/blog/topic/critical-environments), [Building Automation](https://www.setra.com/blog/topic/building-automation), [Calibration](https://www.setra.com/blog/topic/calibration), [HVAC/R](https://www.setra.com/blog/topic/hvac-r)

### Recent Posts

### Posts by Topic

- [Critical Environments (184)](https://www.setra.com/blog/topic/critical-environments)
- [HVAC/R (180)](https://www.setra.com/blog/topic/hvac-r)
- [General Industrial (153)](https://www.setra.com/blog/topic/general-industrial)
- [Building Automation (135)](https://www.setra.com/blog/topic/building-automation)
- [General Industrial OEM (92)](https://www.setra.com/blog/topic/general-industrial-oem)
- [Energy Management (85)](https://www.setra.com/blog/topic/energy-management)
- [Test and Measurement (66)](https://www.setra.com/blog/topic/test-and-measurement)
- [HVAC/R OEM (60)](https://www.setra.com/blog/topic/hvac-r-oem)
- [Barometric (44)](https://www.setra.com/blog/topic/barometric)
- [Alternative Fuels (42)](https://www.setra.com/blog/topic/alternative-fuels)
- [Medical (41)](https://www.setra.com/blog/topic/medical)
- [Process/Mfg Tank Level (40)](https://www.setra.com/blog/topic/process-mfg-tank-level)
- [Water and Wastewater (39)](https://www.setra.com/blog/topic/water-and-wastewater)
- [OHV (38)](https://www.setra.com/blog/topic/ohv)
- [Oil and Gas (35)](https://www.setra.com/blog/topic/oil-and-gas)
- [Industrial Vacuum (29)](https://www.setra.com/blog/topic/industrial-vacuum)
- [Calibration (25)](https://www.setra.com/blog/topic/calibration)
- [Semiconductor (25)](https://www.setra.com/blog/topic/semiconductor)
- [Particle Counting (20)](https://www.setra.com/blog/topic/particle-counting)
- [Cleanroom Monitoring (18)](https://www.setra.com/blog/topic/cleanroom-monitoring)
- [Room Pressure Monitoring (17)](https://www.setra.com/blog/topic/room-pressure-monitoring)
- [Trade Show (12)](https://www.setra.com/blog/topic/trade-show)
- [cleanroom environment (12)](https://www.setra.com/blog/topic/cleanroom-environment)
- [Environmental Monitoring (11)](https://www.setra.com/blog/topic/environmental-monitoring)
- [Power Meters (11)](https://www.setra.com/blog/topic/power-meters)
- [Scales (11)](https://www.setra.com/blog/topic/scales)
- [Healthcare (10)](https://www.setra.com/blog/topic/healthcare)
- [Power Monitoring (10)](https://www.setra.com/blog/topic/power-monitoring)
- [Software (9)](https://www.setra.com/blog/topic/software)
- [cleanroom monitoring systems (9)](https://www.setra.com/blog/topic/cleanroom-monitoring-systems)
- [Case Study (8)](https://www.setra.com/blog/topic/case-study)
- [critical environment technologies (8)](https://www.setra.com/blog/topic/critical-environment-technologies)
- [data centers (8)](https://www.setra.com/blog/topic/data-centers)
- [Humidity (7)](https://www.setra.com/blog/topic/humidity)
- [particle counter (6)](https://www.setra.com/blog/topic/particle-counter)
- [pressure transducers (6)](https://www.setra.com/blog/topic/pressure-transducers)
- [LITE room pressure monitor (5)](https://www.setra.com/blog/topic/lite-room-pressure-monitor)
- [hardware and software cleanroom monitoring systems (5)](https://www.setra.com/blog/topic/hardware-and-software-cleanroom-monitoring-systems)
- [setra lite (5)](https://www.setra.com/blog/topic/setra-lite)
- [Compliance (4)](https://www.setra.com/blog/topic/compliance)
- [Video (3)](https://www.setra.com/blog/topic/video)
- [hospital spaces (3)](https://www.setra.com/blog/topic/hospital-spaces)
- [FAQ & Troubleshooting (2)](https://www.setra.com/blog/topic/faq-troubleshooting)
- [Monitoring Compounding Pharmacies (2)](https://www.setra.com/blog/topic/monitoring-compounding-pharmacies)
- [Semiconductor Manufacturing (2)](https://www.setra.com/blog/topic/semiconductor-manufacturing)
- [agencies that monitor pharmacies (2)](https://www.setra.com/blog/topic/agencies-that-monitor-pharmacies)
- [energy (2)](https://www.setra.com/blog/topic/energy)
- [hvac (2)](https://www.setra.com/blog/topic/hvac)
- [laboratories (2)](https://www.setra.com/blog/topic/laboratories)
- [monitor compound pharmacy (2)](https://www.setra.com/blog/topic/monitor-compound-pharmacy)
- [protected environment (2)](https://www.setra.com/blog/topic/protected-environment)
- [regulatory compliance (2)](https://www.setra.com/blog/topic/regulatory-compliance)
- [setra lite features (2)](https://www.setra.com/blog/topic/setra-lite-features)
- [usp 797 (2)](https://www.setra.com/blog/topic/usp-797)
- [Application Note (1)](https://www.setra.com/blog/topic/application-note)
- [Current Sensors and Transducers (1)](https://www.setra.com/blog/topic/current-sensors-and-transducers)
- [Current Transformers (1)](https://www.setra.com/blog/topic/current-transformers)
- [Lithium-Ion Battery (1)](https://www.setra.com/blog/topic/lithium-ion-battery)
- [Pressure (1)](https://www.setra.com/blog/topic/pressure)
- [aerospace cleanrooms (1)](https://www.setra.com/blog/topic/aerospace-cleanrooms)
- [cems (1)](https://www.setra.com/blog/topic/cems)
- [digital transformation (1)](https://www.setra.com/blog/topic/digital-transformation)
- [ipv6 multicast (1)](https://www.setra.com/blog/topic/ipv6-multicast)
- [ipv6 multicast address (1)](https://www.setra.com/blog/topic/ipv6-multicast-address)
- [ipv6 multicast address range (1)](https://www.setra.com/blog/topic/ipv6-multicast-address-range)
- [isolation room pressure monitoring (1)](https://www.setra.com/blog/topic/isolation-room-pressure-monitoring)
- [multicast address ipv6 (1)](https://www.setra.com/blog/topic/multicast-address-ipv6)
- [multicast ipv6 (1)](https://www.setra.com/blog/topic/multicast-ipv6)
- [operating room (1)](https://www.setra.com/blog/topic/operating-room)
- [pharma 4.0 (1)](https://www.setra.com/blog/topic/pharma-4-0)
- [pressure sensor (1)](https://www.setra.com/blog/topic/pressure-sensor)
- [pressure transducer companies (1)](https://www.setra.com/blog/topic/pressure-transducer-companies)
- [semi conductor (1)](https://www.setra.com/blog/topic/semi-conductor)
- [sensors and transducers (1)](https://www.setra.com/blog/topic/sensors-and-transducers)
- [setra pressure transducers (1)](https://www.setra.com/blog/topic/setra-pressure-transducers)
- [submetering (1)](https://www.setra.com/blog/topic/submetering)
- [sustainability (1)](https://www.setra.com/blog/topic/sustainability)
- [temperature monitor (1)](https://www.setra.com/blog/topic/temperature-monitor)
- [temperature monitoring for pharmacies (1)](https://www.setra.com/blog/topic/temperature-monitoring-for-pharmacies)
- [transducers (1)](https://www.setra.com/blog/topic/transducers)
- [usp 800 (1)](https://www.setra.com/blog/topic/usp-800)
- [water (1)](https://www.setra.com/blog/topic/water)
- [what does hvac stand for (1)](https://www.setra.com/blog/topic/what-does-hvac-stand-for)
- [what is a transducer (1)](https://www.setra.com/blog/topic/what-is-a-transducer)
- [what is hvac (1)](https://www.setra.com/blog/topic/what-is-hvac)

[see all](https://www.setra.com/blog/nasa-technology-streamlines-calibration-process#)

[![HVAC Catalog Cover Image 1](https://www.setra.com/hs-fs/hubfs/HVAC%20Catalog%20Cover%20Image%201.png?width=160&name=HVAC%20Catalog%20Cover%20Image%201.png "HVAC Catalog Cover Image 1")](http://setrasystems.uberflip.com/setra-systems/hvac-catalog-feb-2017)

 

**HVAC Catalog**

 

This comprehensive HVAC Product Catalog is now available online. [Download the PDF now.](http://setrasystems.uberflip.com/setra-systems/hvac-catalog-feb-2017)

 

- [**](https://www.facebook.com/SetraSystems)
- [**](https://twitter.com/setrasystems)
- [**](https://www.youtube.com/user/SetraSystems)
- [**](https://www.linkedin.com/company/setra-systems)
- [**](https://www.instagram.com/setrasystemsinc/)

[Service & Calibration](https://www.setra.com/support/service) | [Products](https://www.setra.com/products) | [Service/RMA](https://www.setra.com/support/service) | [Supplier](https://www.setra.com/support/supplier) | [Customer](https://www.setra.com/support/customer) | [Contact Us](https://www.setra.com/contact-us) | [FAQs](https://faq.setra.com) | [About](https://www.setra.com/about) | [Careers](https://careers.fortive.com/gems-setra/) | [Request Quote](https://www.setra.com/request-a-quote) | [Blog](https://www.setra.com/blog)

 Cookie Settings

159 Swanson Road Boxborough, MA 01719 | [orders@setra.com](mailto:orders@setra.com)

[+1 (978) 263-1400

](tel:+19782631400)

Copyright © 2026 Setra Systems. All Rights Reserved. | [Terms & Conditions](https://www.setra.com/terms-and-conditions) | [Privacy Notice](https://www.setra.com/privacy-policy) | [ISO 9001:2015 Certified | ](https://www.setra.com/hubfs/ISO%20Setra%20LLC%202025.pdf)[Prop 65](https://www.setra.com/prop65) | [Patents](https://www.setra.com/patents) | [Cookies](https://www.setra.com/cookies)

[![Setra Systems Logo](https://www.setra.com/hs-fs/hubfs/setra-systems-logo_white-1.png?width=100&name=setra-systems-logo_white-1.png)](https://www.setra.com/)[![Ralliant logo](https://www.setra.com/hs-fs/hubfs/Ralliant_Logo_SingleColor_White_RGB.png?width=125&name=Ralliant_Logo_SingleColor_White_RGB.png "Setra Systems is a Ralliant Company")](https://www.ralliant.com/)